Specialty Supplements for HSV

The following is a list of supplements known to specifically target the Herpes Simplex Virus and may help to reduce the frequency or severity of herpes outbreaks, unless you have Nervous System Dysregulation. In that case, they may not work optimally to keep HSV in remission. My top three suggestions are quercetin, lysine, and spirulina. Yes, spirulina contains slightly more arginine than lysine, but the benefits far outweigh the risk of being overcautious with this superfood, as long as you don't take it daily. 

Quercetin

 

Studies have shown that quercetin (a flavonol, a type of flavonoid) has antiviral activity against HSV-1, HSV-2, and Shingles. It cuts replication by more than 50%. It also acts against Human Cytomegalovirus (HCMV) and HIV. Quercetin is also reported to help with upper respiratory infections caused by viruses (https://www.quercetin.com). It's also used to relieve allergies triggered by histamine release and for Histamine Intolerance. Those with Viral Cystitis may also benefit from taking quercetin.

 

Foods containing quercetin are capers, red onion, shallots, berries, grapes, kale, broccoli, bell peppers, tomatoes, scallions, Brussels sprouts, cabbage, citrus fruits, red apples, asparagus, buckwheat, black and green tea, elderberry tea, almonds, and pistachios. However, some of these foods may be HSV triggers, and none likely contain high enough doses to ease herpes-related symptoms, although there are many other health benefits to eating these foods.

 

Taking bromelain (200-800 mg daily) can help you better absorb quercetin. You can safely take up to 1000 mg of quercetin daily in divided doses. Taking quercetin on a full stomach is best. You should take quercetin for no more than 12 weeks at a time. 

 

 

L-Lysine

 

Lysine, also known as L-lysine, and arginine are two amino acids found in foods containing protein. Amino acids are the building blocks of proteins that serve to rebuild your bodily tissues. Both play vital roles in maintaining optimal health and wellness. You'll have to contend with these two particular amino acids when living with herpes. Arginine feeds the Herpes Simplex Virus. Lysine blocks arginine's ability to do so. Lysine is also beneficial for reducing stress and anxiety. The idea is to consume foods high in lysine to counteract the effects of arginine. You can learn more here.

 

 

Monlaurin

 

Monolaurin is a dietary supplement derived from lauric acid (a medium-chain fatty acid in coconut and palm oil). Monolaurin has antiviral properties that penetrate the herpes virus biofilm and kill it, resulting in "no more herpes." You may read that it works for all human herpes viruses except genital herpes. Here's the thing. Studies in mice have shown that monolaurin can activate HSV-2, while others have shown the opposite. You can read about those studies here.

 

Monolaurin has few to no side effects, and the FDA has deemed it safe for daily use indefinitely. However, start slowly and work up to the recommended dose to avoid a Herxheimer Reaction (feeling unwell due to viral die-off). Monolaurin kills off harmful bacteria and fungal infections without harming good bacteria.

 

I have to warn you. Monolaurin has a soapy aftertaste, which can be enough to make some people feel nauseous (myself included). I suggest using only pellets, not capsules (capsules might make you burp the taste back up). You'll find a link to my favorite brand, The Ultimate Monolaurin, in The Herpothecary. For tips on dosing, click here. 

 

 

Spirulina

 

Spirulina is a common name for two species of blue-green algae and is considered a superfood because of its high protein and mineral content. It contains trace minerals, exhibits potent antioxidant effects, and contains natural iodine, which has antibacterial, antiviral, antifungal, and antimicrobial properties. Spirulina also contains varying levels of iodine. Many people are deficient in iodine. Adding spirulina to shakes and smoothies is one way to boost overall immunity and maintain healthy iodine levels, which can be depleted by stress. However, excessive or insufficient iodine intake can lead to thyroid problems.  It also contains healthy levels of iron. Spirulina also modulates immune function. Its anti-inflammatory properties inhibit histamine release. Adding spirulina to shakes and smoothies is one way to boost overall immunity.

 

Note: Viruses love iron, so you'll want to use spirulina in moderation. Also, because spirulina contains higher amounts of arginine, which feeds the herpes virus, than lysine, which helps to keep it in check, you may not want to use it as a daily supplement.

 

 

Chlorella 

 

Chlorella is another superfood known to support the immune system and help fight viruses. Spirulina and chlorella are potential remedies for reversing long-term COVID-19 by helping detoxify and nourish the body with minimal to no side effects.

 

Note: Chlorella, like spirulina, contains varying levels of iodine and iron. Viruses love iron, so you'll want to use chlorella in moderation. Additionally, if you have difficulty regulating your iron levels, consult your doctor before using chlorella. 

 

 

Red Marine Algae

 

Red marine algae contain antiviral properties that enhance the immune system and help maintain a proper pH balance. Red algae have been used for centuries to prevent and treat pox-like viruses, including Herpes Simplex Virus. Studies have shown that red marine algae are more effective than Acyclovir, the leading prescription medication, for treating HSV-1 and HSV-2 infections, with no adverse side effects. It can be taken daily as a food supplement. However, because it's an immune stimulant, it may aggravate an autoimmune disorder. Additionally, if you experience heartburn or gastritis, it may be advisable to take it with food or consider a different brand. 

 

Note: In addition to algae, you may be interested in other sea supplements, such as seaweed, a nutrient-dense source of minerals. Nori and wakame are low-histamine seaweeds, compared to other seaweeds, that are usually easily tolerated by most. However, wakame contains higher levels of iron, which can pose problems for those living with certain health conditions. Additionally, viruses "love" an excess of iron. 

 

 

Bee Products

 

Bee Propolis

 

Bee propolis is a resinous substance secreted by honey bees after collecting resin from poplar and conifer buds. They mix this resin with enzymes and beeswax to seal against moisture, fill any unwanted cracks or gaps in the beehive, and improve sanitation. Bees also wrap unwanted insects that enter the hive in propolis to mummify them if they can't remove them. Bee Propolis is a mixture of resin, waxes, essential oils, enzymes, vitamins A and B, flavonoids, minerals, amino acids, and ethanol. Herstat contains bee propolis.

 

Bee propolis has antibacterial, antiviral, antifungal, and anti-inflammatory properties. Bee propolis and bee pollen are potent antivirals and anti-inflammatory agents that help heal burns, blisters, and herpes lesions. It is said to reduce the amount of the herpes virus within the body more so than the prescription medication Acyclovir. However, scientific research on bee propolis is limited. 

 

Propolis is typically brown and grainy, but can also be yellow, green, or even black. It tastes bitter (or sour) and a bit like turpentine.  

 

Applying propolis ointment five times daily may help heal cold sores more quickly and reduce associated pain.

 

Note: Some individuals with bee allergies may also be allergic to bee propolis. Therefore, it is recommended that you perform a patch test before using a bee propolis ointment to determine if it will alleviate your symptoms. Place a dime-sized patch of propolis on the inner arm, cover it with a band-aid, and check after 24 hours for any itching, redness, inflammation, or hives (welts). Do not use bee propolis as part of your wellness regimen if you experience any of the following symptoms. This patch test is only applicable to individuals over two years old. Babies and toddlers under two are at higher risk of severe allergy, as their systems are not yet fully developed to metabolize bee products. If your patch test is negative (no signs of sensitivity), you can begin using propolis ointment by dabbing a small amount onto irritated or broken skin. Ensure you buy a salve or balm (not a tincture or capsule), and always follow the directions listed on your product label. ​

 

 

Bee Pollen 

 

Worker bees collect bee pollen from flowers. Bees mix pollen with nectar and saliva and pack it into honeycomb cells in the beehive. Bee pollen is extremely high in the eight essential amino acids and contains vitamins A, B (all), D, C, E, K, and C, as well as bioflavonoids. Bee pollens come from many different plants, so the contents of bee pollen can vary significantly. Bee pollen has been a source of energy and an anti-aging food for centuries. I haven't tried it myself (I'm allergic to bees). Bee pollen may stimulate the immune system, but its exact mechanism of action needs clarification. It's packed with the vitamins that help reduce stress. If you have an autoimmune disorder, refrain from using bee products until you talk with your doctor. 

 

As long as you aren't allergic to bees, add one teaspoon of bee pollen to 2 teaspoons of pure hot water (not boiling) in a small bowl. Wait a couple of minutes for the pollen to soften, then mash it into a paste with the back of a spoon or pestle. Add one teaspoon of raw honey (Manuka honey is best) and apply it to herpes lesions or any other minor burn with a Q-Tip to moderate the burn. Alternatively, add bee pollen to virgin coconut oil, Saint John's Wort oil, or Tamanu oil (all antiviral), along with a few drops of geranium or lavender essential oil for nerve pain (using 30 drops of essential oils per 2 tablespoons of base oil). You can also add bee pollen to smoothies.

 

 

Royal Jelly

 

Royal jelly is another substance produced by worker honeybees, which is fed to the queen bee to promote her growth and extend her lifespan. It's a complex mixture of proteins, sugars, and fats, rich in B vitamins. Traditionally, people have used royal jelly for skin and hair care, as well as for general tonic support of hormonal balance and energy. A study found that royal jelly reduced the HSV-1 viral load and inhibited cold sore growth.

 

 

 

Turmeric (Curcumin)

 

Curcumin, an active ingredient in turmeric, is said to block the expression of HSV genes by inhibiting certain enzymes that contribute to inflammation and the development of herpes lesions. Curcumin supplements are available online and over the counter. You can also drink turmeric tea. 

 

 

Ashwagandha & Omega-3 Fish Oils

 

Studies show that ashwagandha and omega-3 fish oil supplements can help reduce cortisol levels. Taking these supplements together could help balance stress hormones, potentially reducing the frequency of outbreaks.

 

 

Shiitake Mushroom Extract

 

Shiitake mushroom extract is an immune booster with antiviral properties that prevent HSV from entering host cells. Reishi (see below), Lion's Mane, and Cordyceps mushroom extracts are also immune modulators and may help inhibit the herpes virus. Again, if you have an autoimmune disease, speak with your doctor before using immune-stimulating or immune-modulating supplements.

 

 

Reishi Mushroom Extract

 

Reishi (Ganoderma lucidum), which resembles a toasted, brown, warped pancake in its natural state, is a mushroom used in Traditional Chinese Medicine (TCM) to boost the immune system and combat specific viruses, including influenza and Avian and Swine flu.

 

Reishi is known to help with conditions such as Chronic Fatigue Syndrome, HIV/AIDS, insomnia, and heart and liver disease. But does it work against the Herpes Simplex Virus? Yes, but only when you use it in a specific way. 

 

The parts of the mushroom involved in viral defense are the above-ground parts and the filaments that connect the mushroom groups. In Traditional Chinese Medicine (TCM), reishi mushroom and astragalus (an herb root) are often used together for immune protection. This combination works very well for those with Herpes Simplex Keratitis (a herpes infection of the eye that can cause blindness).

 

Studies show reishi may inhibit the spread of cold sores and genital herpes. It may also help reduce the pain associated with Postherpetic Neuralgia, which is pain experienced once healing has occurred after a severe bout of genital herpes or Shingles.

 

Reishi and other medicinal mushrooms, such as cordyceps, lion's mane, and turkey tail, can be purchased as powders and in tea form. However, placing mushroom powder in a healthy shake or drinking the tea won't be potent enough to prevent a herpes outbreak. Also, taking reishi powder for over one month can be toxic to the liver.

 

During bouts of illness, reishi is best used as a dual-extracted tincture (2 dropperfuls, up to 3 times daily) to help alleviate symptoms of HSV-1 and HSV-2 while lesions are painful. You can also use Reishi against Epstein-Barr Virus (EBV) and HIV. A dual-extracted tincture is made using a combination of water and alcohol. You can make your own or follow the directions on your product's label. I include a recipe for creating a dual-extracted tincture here. You can safely take reishi extract (tincture) for up to one year. Still, do your research to be sure it's safe for you to take. 

 

 

Possible Side Effects

 

  • When reishi is used daily for over three months, it can cause dryness in the nasal passages, mouth, and throat. Other side effects of reishi include itching, rashes, dizziness, headaches, and an upset stomach.

 

  • Do not use reishi if you have low blood pressure (or are on medications to increase it) or have diabetes or an autoimmune disorder.

 

  • Reishi can delay blood clotting, so anyone taking Aspirin, Warfarin (Coumadin), or other medications or supplements that alter blood clotting may be at risk. Don't take reishi with willow bark or other aspirin-like herbs. Stop taking reishi immediately if you develop a bloody nose or have bloody stools.

 

 

  • Not giving reishi to children under 12 is just good advice.

 

Due to the reishi mushroom's potential for side effects, it's not one of my preferred remedies for achieving HSV remission. However, it may be beneficial when used briefly during illness, in conjunction with other mushrooms, and added to decoctions to support overall health.

 

 

Mullein Leaf & Goldenseal

 

Mullein leaf and goldenseal are antiviral herbs. Goldenseal is typically used for acute viral infections of the ears, nose, and throat, including upper respiratory illnesses such as colds, influenza, and COVID-19. However, it can also be helpful against HSV.

 

 

BHT

 

Butylated hydroxytoluene (BHT) is a chemical used as a food preservative. People also use it as medicine, and some say it is anti-aging. BHT is used to treat HSV and AIDS. You can apply it directly to herpes lesions. While it is not a listed carcinogen, some studies have shown it does cause Cancer in animals (lung and liver) and may harm the thyroid gland. It is sold in vitamin stores and on Amazon as an antioxidant. I'm "iffy" on suggesting this touted remedy. I mention it only so that you are aware this option exists. I suggest using it sparingly.

 

 

MSM

 

Methyl sulfonyl methane (MSM) is used to ease the pain of Fibromyalgia Syndrome, which, by the way, can be caused by the Herpes Simplex Virus. MSN is anti-inflammatory and contains antiviral properties. While Fibromyalgia Syndrome is not associated with inflammation (it's more of a nerve signaling problem), the Herpes Simplex Virus has been implicated as a cause. MSM may help in that case. 

 

 

DHEA

 

Chronic nervous system stimulation and an overactive immune system can lead to recurrent herpes outbreaks. Why? Because it causes inflammation. Your body naturally produces the hormone dehydroepiandrosterone (DHEA) in the adrenals. However, DHEA levels decline with age. It drops even faster as a result of chronic stress.

 

Pro-inflammatory cytokines drive chronic inflammation, signal the immune system, and promote cell destruction. DHEA may reduce damage caused by chronic stress and inflammation. It prevents inflammation-causing cytokines from signaling the immune system while also enhancing the immune system's response. DHEA also helps produce other hormones, including estrogen and testosterone. However, taking DHEA is often ignored as a treatment for chronic inflammation.

 

Instead, medical doctors often treat chronic inflammation with synthetic steroids (corticosteroids). Both synthetic steroids and cortisol (a natural stress hormone in the body) trigger herpes outbreaks. Did you catch that? If you take steroids, you have a greater chance of experiencing regular outbreaks. Why? In short bursts, cortisol helps reduce inflammation. However, ongoing or chronic stress elevates cortisol levels, which, in turn, increase inflammation and trigger outbreaks. 

 

 

Phytoestrogens

 

Taking a phytoestrogen supplement or eating foods containing phytoestrogens can help to reduce menopausal and herpes symptoms caused by female ovarian imbalances. ​However, if you are at risk for or have Cancer, don't eat foods containing phytoestrogens or take phytoestrogen supplements without discussing it with your doctor first.

 

 

Note: Some of the foods listed on this page may trigger HSV. However, it's not about cutting any particular food from your diet. Instead, it's about eating snacks and meals with a higher overall lysine content than arginine. My Comprehensive L-Lysine Versus Arginine Food Ratio Guide contains a comprehensive list of lysine and arginine food ratios to check your diet against.

 

 

Also, see Herbal Adaptogens & Antivirals.